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A phase 1b dose escalation study of ipafricept (OMP54F28) in combination with paclitaxel and carboplatin in patients with recurrent platinum-sensitive ovarian cancer

Standard-dose semaglutide may be a good fit for patients who want meaningful weight loss support, prefer a GLP-1-only pathway, are comfortable with gradual titration, and want a balance of effectiveness and tolerability

Diagnoses of pancreatitis increased from 0.17 percent in the year before the first GLP-1 drug prescription to 0.31 percent in the year after for patients who did not have a type 2 diabetes diagnosis

Advertisement Advertisement Inclusion of genomic profiling and risk factors recommended for treatment planning Large retrospective analysis may prompt prospective studies Robust signal from observational study raises prospect of a long-sought medical therapy Post hoc analysis of SURPASS-CVOT trial has implications for future cardiovascular outcome trials Retrospective analysis finds lower mortality rates, fewer hospital visits among patients with Type 1 diabetes using GLP-1 Therapies Observational evidence of neuroprotection with GLP-1 receptor agonists and SGLT-2 inhibitors Study is first to show reduction in autoimmune disease with the common diabetes and obesity drugs Surgical intervention linked to increased lifespan and reduced complications

Morning Versus Evening Injections: What the Evidence Shows Most clinical studies of semaglutide use morning injections, partly because early-day dosing aligns with peak appetite hours and allows patients to observe side effects during waking hours

Identification and quantification of newly synthesized proteins translationally regulated by YB-1 using a novel ClickSILAC approach